carbamazepine will decrease the extent or result of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

Inhibition of platelet aggregation by clopidogrel is entirely because of an Energetic metabolite. Clopidogrel is metabolized to this Energetic metabolite partly by CYP2C19. .

Other Professional medical Challenges The presence of other clinical difficulties might impact using this medication. Ensure that you explain to your medical professional Should you have another medical issues, Primarily:

tecovirimat will boost the stage or effect of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Keep track of. Tecovirimat is really a weak inhibitor of CYP2C8 and CYP2C19. Watch for adverse effects if coadministered with sensitive substrates of such enzymes.

Prevent coadministration of ganaxolone with moderate or solid CYP3A4 inducers. If coadministration unavoidable, think about raising ganaxolone dose; on the other hand, will not exceed maximum daily dose for fat.

Slight (one)modafinil will boost the level or effect of pantoprazole by affecting hepatic enzyme CYP2C19 metabolism. Small/Importance Not known. Net effect on pantoprazole steps not known resulting from opposing outcomes of CYP450 enzymes; watch

sparsentan will minimize the extent or outcome of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep an eye on. Sparsentan (a CYP2C19 inducer) decreases exposure of CYP2C19 substrates and lessens efficacy associated with these substrates.

In situations where by continuous optimistic airway tension (CPAP) would be the treatment method of option for excessive sleepiness, a maximal hard work to take care of with CPAP for an suitable time period must be built before initiating this drug.

crofelemer will increase amounts of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Crofelemer has the possible to inhibit CYP3A4 at concentrations expected within the gut; not likely to inhibit systemically since minimally absorbed.

If an excessive amount is taken, it could come to be pattern-forming. This drugs includes a Medication Information. It is critical which you go through and realize this information and facts. You'll want to more information inquire your doctor about something you do not comprehend.

Girls ought to speak to their Health care service provider about choice beginning Manage options Should they be utilizing a hormonal beginning control system including birth Command tablets, pictures, implants, patches, vaginal rings, and intrauterine devices (IUDs); effective contraception all through use and for one-month following treatment method is suggested; for patients who come to be Expecting throughout procedure, a pregnancy registry is accessible for this drug.

modafinil will lower the extent or result of copyright topical by affecting hepatic enzyme CYP2B6 metabolism. Minimal/Significance Not known.

Keep away from or substitute Yet another drug for these drugs when probable. Examine for lack of therapeutic influence if medication need to be coadministered.

Provigil has not been adequately studied in pregnant Ladies and it really is not known if it is excreted in breast milk. Speak to your doctor prior to breastfeeding. Further Details